abstract：:A 41-year-old patient with mutilating rheumatoid arthritis and progressive systemic sclerosis, who developed a chronic myeloproliferative disorder polycythemia vera was observed. Some of the pathogenetic aspects of this case with special respect to the function abnormalities of peripheral blood polymorphonuclear cells...

journal_title：Zeitschrift fur Rheumatologie

authors： Hrycaj P,Mackiewicz S

更新日期：1992-09-01 00:00:00

abstract：UNLABELLED:102 patients (pat.) with active erosive rheumatoid arthritis (RA) with a median disease duration of only 14 months without malalignment or deformities entered a randomized study to compare the effects of 15 mg methotrexate (MTX) and 50 mg gold sodium thiomalate (GST) administered intramuscularly once a week....

journal_title：Zeitschrift fur Rheumatologie

authors： Herborn G,Rau R,Menninger H,Elhardt D,Schmitt J

更新日期：1992-07-01 00:00:00

abstract：:We saw two cases of infectious sacroiliitis in young patients. The multi-various clinical symptoms, the predispositions, as well as the alteration of laboratory analyses are described. Further, we discuss problems of early diagnosis, diagnostic measures like x-ray, sonography, bone-scan, computerized tomography scan, ...

journal_title：Zeitschrift fur Rheumatologie

authors： Nagler P,Feuerer F,Müller-Fassbender H

更新日期：1992-05-01 00:00:00

abstract：:A central problem of persons with chronic polyarthritis is the necessary adaptation to deteriorating health in everyday activities. Difficulties and burdens of this adaptation are parts of the study undertaken in the Unna Model, which was part of the research on "Local Services for CP-Patients". In the first part two ...

journal_title：Zeitschrift fur Rheumatologie

authors： Grunow-Lutter V,Grunow D

更新日期：1992-01-01 00:00:00

abstract：:409 unselected outpatients were asked standardized expert system questions on the medical history of joint complaints. An average number of 30.4 +/- 6.6 out of 60 questions with 346 different answers were asked in a mean time of 20.1 +/- 6.6 min. This time, required for the questions to be displayed on the computer sc...

journal_title：Zeitschrift fur Rheumatologie

authors： Schewe S,Krüger K,Herzer P,Schattenkirchner M

更新日期：1991-07-01 00:00:00

abstract：:Bone metabolic homeostasis is regulated by a number of hormones and local modulators, and the study of these factors has been of major help in our understanding of bone disease. However, these parameters do not, in a strict sense reflect the metabolic and biochemical changes in the diseased bone tissue. Thus, there is...

journal_title：Zeitschrift fur Rheumatologie

authors： Tohmé JF,Seibel MJ,Silverberg SJ,Robins SP,Bilezikian JP

更新日期：1991-05-01 00:00:00

abstract：:Three days after cholecystectomy, seven patients received a single dose of auranofin (5 tablets Ridaura = 4.35 mg gold). At defined time points thereafter the gold content in samples of blood, plasma, urine, bile, and feces was determined by instrumental neutron activation analysis (INAA). Maxima of the mean gold conc...

journal_title：Zeitschrift fur Rheumatologie

authors： Benn HP,Schnier C,Bauer E,Seiler KU,Elhöft H,Löffler H

更新日期：1991-01-01 00:00:00

abstract：:NSAIDs, including acetylsalicylic acid, are frequently classified as peripherally-acting analgesics. This is based on the fact that these substances, among other effects, inhibit the biosynthesis of prostaglandines. A few solid arguments, however, stand against an exclusively peripheral mode of the analgesic action of...

journal_title：Zeitschrift fur Rheumatologie

authors： Jurna I

更新日期：1991-01-01 00:00:00

abstract：:The generalized tendomyopathy (fibromyalgia) is characterized by the characteristic picture of multilocular pain symptoms, severe pressure-type pain in the tendon insertions and muscles, vitality deficiency, sleep disturbance and other vegetative disorders as well as functional complaints and is often also characteriz...

journal_title：Zeitschrift fur Rheumatologie

authors： Brückle W,Lautenschläger J,Müller W

更新日期：1991-01-01 00:00:00

abstract：:Twelve patients with osteoarthrosis were locally treated with Felbinac Gel (biphenyl acetic acid (BPAA) 3%) three times daily for 14 days (five patients), 28 days (six patients) or 42 days (one patient) before elective knee joint surgery. BPAA plasma concentrations as of the seventh day of treatment were steady at bet...

journal_title：Zeitschrift fur Rheumatologie

authors： Bolten W,Waldorf-Bolten E,Sarfert D,Lehmann W,Miehlke W

更新日期：1990-11-01 00:00:00

abstract：:Rehabilitation activities belong to tertiary prevention. The latter includes all measures that aim at avoiding the progression of a physical disability to a handicap, or those that diminish the extent of the handicap. Complex rehabilitation programs represent a cooperation of medical, occupational, and social reintegr...

journal_title：Zeitschrift fur Rheumatologie

authors： Wessel G,Leistner K

更新日期：1990-09-01 00:00:00

abstract：:Fifty-seven patients with rheumatoid arthritis were examined clinically, radiologically, and by means of transcranial magnetic brain stimulation. With this method central motor conduction times of the corticospinal pathways can be measured. The aim of the study was to compare the different methods to detect a cervical...

journal_title：Zeitschrift fur Rheumatologie

authors： Theiler R,Dvorak J,Janssen B,Baumgartner H,Herdmann J

更新日期：1990-09-01 00:00:00

abstract：:Involvement of the musculoskeletal system in 50 Lyme borreliosis patients seen in Czechoslovakia is described. Thirty-three patients reported tick bites or that they had removed a tick, four patients had been bitten by some other insect. Skin reaction following tick bite were found in 29 patients. Neurologic involveme...

journal_title：Zeitschrift fur Rheumatologie

authors： Valesová M,Trnavský K

更新日期：1990-07-01 00:00:00

abstract：:The present study examined relations between irrational attitudes and pain experience in patients with rheumatoid arthritis (RA). 128 patients with definite RA from a rheumatic treatment center were studied by administration of the Irrational Attitudes Questionnaire (15) and a revised form of the Multidimensional Pain...

journal_title：Zeitschrift fur Rheumatologie

authors： Klages U

更新日期：1990-05-01 00:00:00

abstract：:The diagnosis of chondrocalcinosis is based on typical radiographic findings and synoviaanalysis. We examined 10 patients with chondrocalcinosis to see whether pathognomonic findings of the disease could also be seen by ultrasound. Ultrasound and x-ray findings were compared. Calcifications of the knee menisci were se...

journal_title：Zeitschrift fur Rheumatologie

authors： Kellner H,Zoller W,Herzer P

更新日期：1990-05-01 00:00:00

abstract：:A set of early diagnostic (ED) criteria comprising clinical data, ESR, radiological spinal signs, and the risk factor HLA B27 was evaluated after 5 and 10 years in a follow-up of 54 patients with an initial diagnosis of possible ankylosing spondylitis (AS). After 10 years 32 patients (59%) had developed definite AS ac...

journal_title：Zeitschrift fur Rheumatologie

authors： Mau W,Zeidler H,Mau R,Majewski A,Freyschmidt J,Stangel W,Deicher H

更新日期：1990-03-01 00:00:00

abstract：:The influence of the oxicams, a special group of non-steroidal anti-inflammatory drugs, to the sister chromatid exchange (SCE) was determined on human lymphocytes in vitro and in vivo. The analysis of SCE is a sensitive parameter indicating chromosomal damage. The cytogenetic examinations of Lornoxicam, Tenoxicam, and...

journal_title：Zeitschrift fur Rheumatologie

authors： Kullich W,Hermann J,Klein G

更新日期：1990-03-01 00:00:00

abstract：:The effect of recombinant interleukin-2 (IL-2) on proliferative and cytotoxic response of peripheral blood mononuclear cells (PBMC) was investigated in a group of 21 patients with systemic lupus erythematosus (SLE). There was a significant decrease in thymidine uptake of peripheral blood mononuclear cells when compare...

journal_title：Zeitschrift fur Rheumatologie

authors： Jira M,Strejcek J,Zavadil Z,Antosova E,Rejholec V

更新日期：1990-01-01 00:00:00

abstract：:Tendomyopathies (TM) comprise two subgroups. Both are caused by the irritation of nociceptors (IN). Type I results from IN within muscles and tendons with the consequence of local pain, whereas type II refers to TM occurring at a site distant from IN anywhere in the body. Such TM-type II are understood to serve for th...

journal_title：Zeitschrift fur Rheumatologie

authors： Menninger H,Hiemeyer K

更新日期：1989-11-01 00:00:00

abstract：:The neonatal lupus erythematosus syndrome, first described by McCuistion and Schoch in 1954, is associated with characteristic skin lesions and congenital heart block in the new-born, and the presence of Ro-(SSA), La-(SSB), or RNP antibodies in mothers and infants. A transplacental transference of maternal autoantibod...

journal_title：Zeitschrift fur Rheumatologie

authors： Mayet WJ,Hermann E,Bachmann M,Poralla T,Meyer zum Büschenfelde KH

更新日期：1989-03-01 00:00:00

abstract：:The Churg-Strauss syndrome is a disorder characterized by hypereosinophilia and systemic vasculitis occurring in patients with asthma and allergic rhinitis. Only few patients are identified as having this syndrome. The three histological criteria are necrotizing vasculitis, tissue infiltration by eosinophils, and extr...

journal_title：Zeitschrift fur Rheumatologie

authors： Stockmann G

更新日期：1988-11-01 00:00:00

abstract：:In a sequential study the pathogenesis of chronic polyarthritis occurring spontaneously in MRL mice was analysed by light microscopy. A total of 128 MRL mice of both substrains (MRL/Mp-lpr/lpr and +/+) and different age groups was studied. In 50 lpr/lpr mice, tinctorial and histochemical methods were applied for the i...

journal_title：Zeitschrift fur Rheumatologie

authors： Hewicker M,Garcés LH,Kromschröder E,Trautwein G

更新日期：1988-07-01 00:00:00

abstract：:Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by, among other things, spinal and extraspinal manifestations. Two studies on the prevalence and clinical significance of hyperostotic spurs and ectopic ossifications in the pelvic area are presented. Spinal DISH seems to be a risk factor for the develop...

journal_title：Zeitschrift fur Rheumatologie

authors： Fahrer H,Koch P,Barandun R,Gerber NJ

更新日期：1988-07-01 00:00:00

abstract：:The supernatant of peripheral blood monocytes, cultured with autologous sera from patients with rheumatoid arthritis, stimulates healthy human granulocytes to significantly elevated chemiluminescence (p = 0.05) compared with supernatants of monocytes from osteoarthritic patients or healthy volunteers. Cultures without...

journal_title：Zeitschrift fur Rheumatologie

authors： Meske S,Bänziger E

更新日期：1988-05-01 00:00:00

abstract：:Temporomandibular joint affections in rheumatic disease are described. They were seen in inflamed joint diseases, mostly in rheumatoid arthritis, and less so in juvenile rheumatoid arthritis, psoriatic arthritis, Reiter's syndrome, ankylosing spondylitis, and collagen vascular disease. In osteoarthrosis, the temporoma...

journal_title：Zeitschrift fur Rheumatologie

authors： Wörth WD,Keller B,Graber G,Müller W

更新日期：1988-03-01 00:00:00

abstract：:Ha(La)-antibodies are detected by counterimmunoelectrophoresis (CIE) in sera of systemic lupus erythematosus (SLE) patients, but not in sera of patients with progressive systemic scleroderma (PSS) (n = 38), rheumatoid arthritis (n = 91), ankylosing spondylitis (n = 97), and other rheumatic diseases (n = 452). This ant...

journal_title：Zeitschrift fur Rheumatologie

authors： Lakomek HJ,Wagener S,Schwochau M,Krüskemper HL

更新日期：1988-03-01 00:00:00

abstract：:A multicentric post-marketing surveillance study over 7 years including 5,124 patients is presented. According to clinical and laboratory data, the drug D-penicillamine was effective, with a tendency of loss of efficacy after therapy of 5 years or longer. Response was better in the early stage of the disease. Side eff...

journal_title：Zeitschrift fur Rheumatologie

authors： Kashiwazaki S

更新日期：1988-01-01 00:00:00

abstract：:Commonly-used serological methods for the determination of Yersinia antibodies are based on the presence of agglutinins, which are frequently absent or of low titer when arthritis begins. Stool cultures are usually negative at that time, so many Yersinia infections are underdiagnosed. On the other hand, significant ag...

journal_title：Zeitschrift fur Rheumatologie

authors： Grasedyck K,Heesemann J

更新日期：1987-07-01 00:00:00

abstract：:We report on a 39-year-old male patient suffering from seropositive rheumatoid arthritis who developed severe colitis during oral gold (Auranofin) therapy. So far, two further cases of colitis during oral, and 28 cases of enterocolitis during parenteral chrysotherapy have been described. The pathomechanism has not bee...

journal_title：Zeitschrift fur Rheumatologie

authors： Bross-Bach U,Saal JG,Hartmann F,Müller CA,Waller HD

更新日期：1987-07-01 00:00:00

abstract：:Sulfasalazine was used as second line agent in 15 children with different forms of rheumatoid arthritis. In 9 cases amelioration could be achieved with respect to clinical symptoms as well as laboratory parameters. Thus, sulfasalazine can be recommended as basic medication also in juvenile rheumatoid arthritis. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Suschke HJ

更新日期：1987-03-01 00:00:00

abstract：:An attempt is made to compile the pharmacological data on the leading non-steroidal anti-inflammatory drugs. They concern the pharmacodynamics, the pharmacokinetics and the unwanted effects of these compounds. From these data a few suggestions for rational use are made: Ibuprofen and diclofenac present as drugs with s...

journal_title：Zeitschrift fur Rheumatologie

authors： Brune K

更新日期：1987-01-01 00:00:00

abstract：:Inflammatory myopathies are as a rule rare diseases of skeletal muscle. In the majority of cases noninfective autoimmunological reactions are assumed. Only few diseases have an infectious origin. From a myopathological point of view, polymyositis must be selected from interstitial nodular myositis. The most important ...

journal_title：Zeitschrift fur Rheumatologie

authors： Pongratz D

更新日期：1986-07-01 00:00:00

abstract：:Since 1978 a 63-year-old woman with rheumatoid arthritis received D-penicillamine (D-PA) in a daily dose of 250-500 mg (mean 300 mg/d). In 1982 the patient complained of diplopia for several days, the ophthalmological and neurological examinations three days later were normal. In July 1983 she developed a myasthenic s...

journal_title：Zeitschrift fur Rheumatologie

authors： Kolarz G,Maida EM

更新日期：1986-05-01 00:00:00

abstract：:In a twenty-nine year old female patient with progressive systemic sclerosis (scleroderma) (PSS) and an impressing involvement of the intestine (disturbance of the oesophageal motility, pseudo-obstruction, malabsorption) a spontaneous, asymptomatic pneumoperitoneum is observed. Perforation or pneumatosis cystoides int...

journal_title：Zeitschrift fur Rheumatologie

authors： Lang B,Meske S,Billmann P,Vaith P,Peter HH

更新日期：1986-03-01 00:00:00

abstract：:Fabry's disease is a hereditary lipid storage disease with deposition of ceramides in nearly all tissues. The lipid deposition in the skin and the synovial compartments causes an enlargement of the skin, the joint capsules and the tendon sheaths, which are recognizable by low KV radiography. The bones of the hand main...

journal_title：Zeitschrift fur Rheumatologie

authors： Fischer E

更新日期：1986-01-01 00:00:00

abstract：:Activated monocytes/macrophages secrete monokines, regulatory proteins which are capable of initiating and maintaining immune processes as well as having an effect on other non immunocompetent cells. In rheumatoid arthritis the monokine Interleukin-1 (IL-1) was detected in the synovial fluid. IL-1 activates immunocomp...

journal_title：Zeitschrift fur Rheumatologie

authors： Hermann E,Müller W

更新日期：1985-09-01 00:00:00

abstract：:We tested the efficacy of the immunomodulator Bestatin, which has been successfully applied in Japan, in a preliminary open study in ten patients with classical or definite rheumatoid arthritis. Patients whose arthritis was characterized by a low humoral activity showed a partial remission of the disease after six mon...

journal_title：Zeitschrift fur Rheumatologie

authors： Meske S,Vogt P,Maly FE,Seitz M,Müller W

更新日期：1985-09-01 00:00:00

abstract：:The difference between mofebutazone and phenylbutazone is shown by means of toxicological, pharmacological and pharmacokinetic studies as well as by the protein binding. In spite of a certain chemical similarity both substances differ distinctly. Mofebutazone is approx. 5-6 times less toxic than phenylbutazone but its...

journal_title：Zeitschrift fur Rheumatologie

authors： Loew D,Schuster O,Knoell HE,Graul EH

更新日期：1985-07-01 00:00:00

abstract：:The pressure load is critical for vascular wall alteration. Systolic blood pressure was measured by Doppler sonography in the finger and arm arteries of 24 patients with rheumatoid arthritis and compared to a control group (n = 22) of nearly the same age. The transmitter frequency of the ultrasound probe was 9.6 MHz. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Beste KW

更新日期：1985-05-01 00:00:00

abstract：:42 patients with definite or classic rheumatoid arthritis were treated with an enzyme mixture (Wobenzym) for 6 weeks. Circulating immune complexes were investigated with a Clq-solid phase RIA in weekly intervals and also rheumatoid factors were determined together with other routine laboratory tests. The condition of ...

journal_title：Zeitschrift fur Rheumatologie

authors： Steffen C,Smolen J,Miehlke K,Hörger I,Menzel J

更新日期：1985-03-01 00:00:00